Rong Wang
Rong Wang, PhD
Founder & Managing Director, EGGXPERT B.V., The Netherlands
Guest Researcher, Aachen-Maastricht Biobased Materials, Maastricht University, The Netherlands
Tel: (+31) 645036469
Email: r.wang@eggxpert.nl
Biography:
During 2012-2016, Rong Wang did her PhD thesis project - “Cartilage regeneration by injectable hydrogels” in Twente University, where she was the main research scientist for a start-up company Hy2care B.V.
From 2016, before stepping into business ventures, she was a post-doc researcher working in MERLN Institute for Technology-Inspired Regenerative Medicine, under the leadership of Prof. Lorenzo Moroni and Prof. dr. Clemens van Blitterswijk in Maastricht University. She’s working on design and preparation of bio-inductive materials for digital light processing (DLP) fabrication for soft tissue regeneration.
Influenced by entrepreneurial environment both in Twente University and MERLN institute, she is fascinating on efforts in driving clinical-directed biomaterials, as well with strong driven force on translating bio-organic materials/innovations to market. In May 2018, interrupted by attempts in developing more applicable science, she quit her post-doc position within university and initiated an innovative project working on creation added value to industrial biowaste – eggshells (including eggshell membranes and eggshells). The project was successfully founded by province and national subsidies and local Rabobank innovation loan.
Dr. Rong Wang is an entrepreneur with scientific-driven spirit. She’s fascinating in 3D printing technology since late of her PhD research. She has a dream to bridge the materials with human lifestyle by the technologies of additive manufacturing.
Abstract:
Choice of bioinks: synthetic or natural materials or combination
3D bioprinting has provided particular cellularized constructs for human tissues regeneration. This technology enables the process flexibility, versatility and all-in-one manufacturing through the design of smart and advanced biomaterials and proper polymerization techniques [1]. An ideal bioink should possess proper mechanical, rheological, and biological properties of the target tissues, which are critical to ensure correct functionalities. Therefore, it heavily relies on biomaterials for structural support and sites for attachment of biological and mechanical cues of the laboratory-engineered tissue constructs and organs.
Hydrogels are the most adequate candidates of biomaterials because they have many similar features of the natural extracellular matrix and could also provide a highly hydrated environment for cell proliferation. However, the vast majority of bioinks present limitations in the printing of chemically defined 3D constructs with controllable biophysical and biochemical properties. In this field of bio-fabrication, particularly in bioprinting, the lack of suitable hydrogels remains a major challenge [2]. Thus, choosing appropriate hydrogels for bioprinting is the key to print self-supporting 3D constructs.
Hydrogels in tissue engineering are classi?ed into two groups: naturally-derived hydrogels such as gelatin, ?brin, collagen, chitosan, and alginate and synthetically-derived hydrogels such as Pluronic or polyethylene glycol (PEG) [3]. Naturally-derived hydrogels generally possess inherent signaling molecules for cell adhesion, while synthetically-derived hydrogels stand with bioprintability and mechanical support for shape maintenance and load bearing.
A comprehensive of understanding of pros & cons gives you the best choice of your bioink for your particular tissue applications.
Founder & Managing Director, EGGXPERT B.V., The Netherlands
Guest Researcher, Aachen-Maastricht Biobased Materials, Maastricht University, The Netherlands
Tel: (+31) 645036469
Email: r.wang@eggxpert.nl
Biography:
During 2012-2016, Rong Wang did her PhD thesis project - “Cartilage regeneration by injectable hydrogels” in Twente University, where she was the main research scientist for a start-up company Hy2care B.V.
From 2016, before stepping into business ventures, she was a post-doc researcher working in MERLN Institute for Technology-Inspired Regenerative Medicine, under the leadership of Prof. Lorenzo Moroni and Prof. dr. Clemens van Blitterswijk in Maastricht University. She’s working on design and preparation of bio-inductive materials for digital light processing (DLP) fabrication for soft tissue regeneration.
Influenced by entrepreneurial environment both in Twente University and MERLN institute, she is fascinating on efforts in driving clinical-directed biomaterials, as well with strong driven force on translating bio-organic materials/innovations to market. In May 2018, interrupted by attempts in developing more applicable science, she quit her post-doc position within university and initiated an innovative project working on creation added value to industrial biowaste – eggshells (including eggshell membranes and eggshells). The project was successfully founded by province and national subsidies and local Rabobank innovation loan.
Dr. Rong Wang is an entrepreneur with scientific-driven spirit. She’s fascinating in 3D printing technology since late of her PhD research. She has a dream to bridge the materials with human lifestyle by the technologies of additive manufacturing.
Abstract:
Choice of bioinks: synthetic or natural materials or combination
3D bioprinting has provided particular cellularized constructs for human tissues regeneration. This technology enables the process flexibility, versatility and all-in-one manufacturing through the design of smart and advanced biomaterials and proper polymerization techniques [1]. An ideal bioink should possess proper mechanical, rheological, and biological properties of the target tissues, which are critical to ensure correct functionalities. Therefore, it heavily relies on biomaterials for structural support and sites for attachment of biological and mechanical cues of the laboratory-engineered tissue constructs and organs.
Hydrogels are the most adequate candidates of biomaterials because they have many similar features of the natural extracellular matrix and could also provide a highly hydrated environment for cell proliferation. However, the vast majority of bioinks present limitations in the printing of chemically defined 3D constructs with controllable biophysical and biochemical properties. In this field of bio-fabrication, particularly in bioprinting, the lack of suitable hydrogels remains a major challenge [2]. Thus, choosing appropriate hydrogels for bioprinting is the key to print self-supporting 3D constructs.
A comprehensive of understanding of pros & cons gives you the best choice of your bioink for your particular tissue applications.