Dong-Woo Cho
Dong-Woo Cho, Ph.D.
Nam-go Chair Professor
Department of Mechanical Engineering
Pohang University of Science and Technology
dwcho@postech.ac.kr
Biography:
Prof. Dong-Woo Cho received his Ph.D. in Mechanical Engineering from the University of Wisconsin-Madison in 1986. Ever since, he has been a professor of Department of Mechanical Engineering at the Pohang University of Science and Technology. He is director of the Center for Rapid Prototyping-based 3D Tissue/Organ printing. His research interests include 3D microfabrication based on 3D Printing technology, its application to tissue engineering, and more generally to bio-related fabrication. He has recently focused on tissue/organ printing technology and development of high-performance bio-inks. He has received several prestigious awards in these academic areas. He serves or has served on the editorial boards of several International Journals. Prof. Cho has published over 240 academic papers in various international journals in the field of manufacturing and tissue engineering, and has contributed chapters to ten books and written a textbook related to tissue engineering and organ printing.
Selected Publications
1. Falguni Pati, Jinah Jang, Dong-Heon Ha, Sung Won Kim, Jong-Won Rhie, Jin-Hyung Shim, Deok-Ho Kim, Dong-Woo Cho, “Printing three dimensional tissues with decellularized extracellular matrix bioink,” Nature Communications, Vol.5, Article No.3935, pp.1-11, June 2014.
2. Sanskrita Das, Falguni Pati, Yeong-Jin Choi, Girdhari Rijal, Jin-Hyung Shim, Alok R. Ray, Dong-Woo Cho, Sourabh Ghosh, “Bioprintable, cell-laden silk fibroin-gelatin hydrogel supporting multilineage differentiation of stem cells for fabrication of 3D tissue constructs,” Acta Biomaterialia, Vol.11, pp.233-246, January 2015.
3. Ju Young Park, Jin-Hyung Shim, Song-Ah Choi, Jinah Jang, Myungshin Kim, Sang Hwa Lee, Dong-Woo Cho, “Spatial and temporal control of dual growth factors (BMP-2 and VEGF) using 3D printing technology for vascularized large volume bone regeneration,” Journal of Materials Chemistry B, Vol.3, pp.5415-5425, July 2015.
4. Falguni Pati, Tae-Ha Song, Girdhari Rijal, Jinah Jang, Sung Won Kim, Dong-Woo Cho, “Ornamenting 3D printed scaffolds with cell-laid extracellular matrix for bone tissue regeneration,” Biomaterials, Vol.37, pp.230-241, January 2015.
5. Jeong Hun Park, Jung Min Hong, Young Min Joo, Jin Woo Jung, Sang-Jin Lee, James J. Yoo, Sung Won Kim, Dong-Woo Cho, “A novel tissue-engineered trachea and its relevant mechanical behavior,” Biomaterials, Vol.62, pp.106-115, September 2015.
6. Falguni Pati, Dong-Heon Ha, Jinah Jang, Hyun Ho Hahn, Jong-Won Rhie, Dong-Woo Cho, “Biomimetic 3D Tissue Printing for Soft Tissue Regeneration,“ Biomaterials, Vol.62, pp.164-175, September 2015.
Abstract:
3D Printing Technology with Tissue Specific Bioinks
The research at the Intelligent Manufacturing Systems Laboratory is in the application of 3D printing technology to the field of biomedical engineering by fabricating com-plex 3D structures. Specifically, the 3D printing technology lies at the basis of the re-search for the development of tissue regeneration and in vitro testing platforms that relate to the big picture of tissue engineering and regenerative medicine. Beyond the fabrication of 3D scaffolds, the laboratory has now developed a 3D cell/tissue printing technology for the fabrication of live scaffolds of which the integrated pre-tissues can be fabricated in a single step with the use of multiple types of cells and biological ma-terials. In addition, the laboratory has also developed tissue- and organ- derived extra-cellular matrix bioink that would optimize the mimicry of the native tissue’s biochemi-cal microenvironments and enhance pre-tissues functionalities. Taken together, the re-search done at the IMS laboratory includes the development of composite cell-based scaffolds for the treatment of areas of defects and hard-to-cure diseases through the help of cell/tissue printing technology and bioink. The lab also works on the develop-ment of in vitro testing models including organ-on-a-chip, and is steered towards the actual clinical application and new drug discovery. The following presentation will demonstrate the role and significance of 3D cell printing rather than ordinary 3D printing in the biomedical field and provide us with a time for deep discussions on the aforementioned research topics.
Figure 1 Printed structures with various Tissue specific dECM bioinks
Nam-go Chair Professor
Department of Mechanical Engineering
Pohang University of Science and Technology
dwcho@postech.ac.kr
Biography:
Prof. Dong-Woo Cho received his Ph.D. in Mechanical Engineering from the University of Wisconsin-Madison in 1986. Ever since, he has been a professor of Department of Mechanical Engineering at the Pohang University of Science and Technology. He is director of the Center for Rapid Prototyping-based 3D Tissue/Organ printing. His research interests include 3D microfabrication based on 3D Printing technology, its application to tissue engineering, and more generally to bio-related fabrication. He has recently focused on tissue/organ printing technology and development of high-performance bio-inks. He has received several prestigious awards in these academic areas. He serves or has served on the editorial boards of several International Journals. Prof. Cho has published over 240 academic papers in various international journals in the field of manufacturing and tissue engineering, and has contributed chapters to ten books and written a textbook related to tissue engineering and organ printing.
Selected Publications
1. Falguni Pati, Jinah Jang, Dong-Heon Ha, Sung Won Kim, Jong-Won Rhie, Jin-Hyung Shim, Deok-Ho Kim, Dong-Woo Cho, “Printing three dimensional tissues with decellularized extracellular matrix bioink,” Nature Communications, Vol.5, Article No.3935, pp.1-11, June 2014.
2. Sanskrita Das, Falguni Pati, Yeong-Jin Choi, Girdhari Rijal, Jin-Hyung Shim, Alok R. Ray, Dong-Woo Cho, Sourabh Ghosh, “Bioprintable, cell-laden silk fibroin-gelatin hydrogel supporting multilineage differentiation of stem cells for fabrication of 3D tissue constructs,” Acta Biomaterialia, Vol.11, pp.233-246, January 2015.
3. Ju Young Park, Jin-Hyung Shim, Song-Ah Choi, Jinah Jang, Myungshin Kim, Sang Hwa Lee, Dong-Woo Cho, “Spatial and temporal control of dual growth factors (BMP-2 and VEGF) using 3D printing technology for vascularized large volume bone regeneration,” Journal of Materials Chemistry B, Vol.3, pp.5415-5425, July 2015.
4. Falguni Pati, Tae-Ha Song, Girdhari Rijal, Jinah Jang, Sung Won Kim, Dong-Woo Cho, “Ornamenting 3D printed scaffolds with cell-laid extracellular matrix for bone tissue regeneration,” Biomaterials, Vol.37, pp.230-241, January 2015.
5. Jeong Hun Park, Jung Min Hong, Young Min Joo, Jin Woo Jung, Sang-Jin Lee, James J. Yoo, Sung Won Kim, Dong-Woo Cho, “A novel tissue-engineered trachea and its relevant mechanical behavior,” Biomaterials, Vol.62, pp.106-115, September 2015.
6. Falguni Pati, Dong-Heon Ha, Jinah Jang, Hyun Ho Hahn, Jong-Won Rhie, Dong-Woo Cho, “Biomimetic 3D Tissue Printing for Soft Tissue Regeneration,“ Biomaterials, Vol.62, pp.164-175, September 2015.
Abstract:
3D Printing Technology with Tissue Specific Bioinks
The research at the Intelligent Manufacturing Systems Laboratory is in the application of 3D printing technology to the field of biomedical engineering by fabricating com-plex 3D structures. Specifically, the 3D printing technology lies at the basis of the re-search for the development of tissue regeneration and in vitro testing platforms that relate to the big picture of tissue engineering and regenerative medicine. Beyond the fabrication of 3D scaffolds, the laboratory has now developed a 3D cell/tissue printing technology for the fabrication of live scaffolds of which the integrated pre-tissues can be fabricated in a single step with the use of multiple types of cells and biological ma-terials. In addition, the laboratory has also developed tissue- and organ- derived extra-cellular matrix bioink that would optimize the mimicry of the native tissue’s biochemi-cal microenvironments and enhance pre-tissues functionalities. Taken together, the re-search done at the IMS laboratory includes the development of composite cell-based scaffolds for the treatment of areas of defects and hard-to-cure diseases through the help of cell/tissue printing technology and bioink. The lab also works on the develop-ment of in vitro testing models including organ-on-a-chip, and is steered towards the actual clinical application and new drug discovery. The following presentation will demonstrate the role and significance of 3D cell printing rather than ordinary 3D printing in the biomedical field and provide us with a time for deep discussions on the aforementioned research topics.
Figure 1 Printed structures with various Tissue specific dECM bioinks